Mastitis

Mastitis continues to be a commonly occurring and economically detrimental disease in the dairy industry. The negative effects of clinical mastitis regarding pain and discomfort are most likely underestimated, and therefore, animal welfare is compromised.

Pain management therapy with a nonsteroidal anti-inflammatory drug (NSAID) such as Metacam can reduce the clinical signs of mastitis.1,2 In addition, research reported improvements in milk yield, reduction in somatic cell counts (SCC), and decrease in culling risk when Metacam was used to treat cases of clinical mastitis.3,1

University of Guelph researchers looked at the effect of Metacam on pain sensitivity, rumination time and clinical signs in dairy cows with endotoxin-induced clinical mastitis.4
Compared with the placebo cattle, the Metacam-treated group demonstrated significantly (P<0.05):

  • Less pain pressure sensitivity
  • Lower udder edema score (i.e., less local inflammation)
  • Lower body temperature following the onset of systemic signs of mastitis

There was a tendency for reduction of acute-phase protein (haptoglobin). In addition, study cows treated with Metacam maintained dry-matter intake.

Based on the results of this study, it was concluded that a single treatment of Metacam was effective in reducing the pain, inflammation and fever associated with clinical bovine mastitis.

References:
1. Banting A, et al. Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. Vet Rec 2008;163(17):506–509.

2. Friton GM, et al. Evaluation of the economic benefit of a systemic treatment with the NSAID meloxicam (Metacam) in endotoxin-induced bovine clinical mastitis, in Proceedings. IDF Congress; Maastricht, Pays-Bas.

3. McDougall S, Bryan MA, Tiddy RM, et al. Effect of treatment with the nonsteroidal anti-inflammatory meloxicam on milk production, somatic cell count, probability of re-treatment and culling of dairy cows with mild clinical mastitis. J Dairy Sci 2009;92(9):4421–4431.

4. Fitzpatrick CE, Chapinal N, Petersson-Wolfe CS, et al. The effect of meloxicam on pain sensitivity, rumination time and clinical signs in dairy cows with endotoxin-induced clinical mastitis. J Dairy Sci 2013;96(5):2847–2856.

WARNING: MILK TAKEN FROM TREATED ANIMALS WITHIN 96 HOURS AFTER TREATMENT MUST NOT BE USED IN FOOD.